Which SARMs Results To Expect
During the past few years, SARMs have become extremely popular. The majority of people do not seem to know exactly what they are or what they’re capable of doing.
There are numerous misconceptions surrounding these compounds. As a result, they have become an essential point of debate among fitness enthusiasts. People are concerned whether these substances are effective and whether or not they are safe. Again, they are often compared to anabolic steroids, in a bid to gauge their muscle-building potential.
The following review will demonstrate the kind of results to expect when using SARMs. In particular, you will learn what to expect in muscle mass increase.
However, before delving deeper into the effects of SARMs and their muscle-building potential, a slight background of the substances will help to provide some context.
What are SARMs?
The word SARMs is a short form for selective androgen receptor modulators. Majority of the SARMs were first introduced into mainstream science during the ‘90s. Over the years, steroidal SARMs have been used for therapeutic purposes to treat various conditions such as cancer, osteoporosis, hypogonadism, and a host of other ailments known to cause muscle and bone wasting. However, these substances were later found to contain considerable muscle building potential.
When SERMs (Selective Estrogen Receptor Modulators) were sanctioned for treating hormone receptor-positive breast cancer in postmenopausal women, it was welcomed as one of the most significant medical developments of the 21st century. On the other end of the spectrum lay SARMs which were and are still believed to be the solution to most of the lifestyle diseases plaguing humankind today. That includes anorexia, cachexia, hypoglycemia, testosterone replacement, hyperlipidemia, among others.
SARMs are still under research for therapeutic application. However, members of the bodybuilding community are already experimenting with them and providing sound data on their effectiveness on performance enhancement.
How Do Sarms Work?
This is a significant question posed by bodybuilders daily.
Cells in various parts of the human body contain androgen receptors. SARMs signal the androgen receptors to amplify their activity in a similar way to anabolic steroids. However, unlike anabolic steroids, SARMs are selective in their action.
For instance, LGD-4033 is touted to be one of the best, if not the best SARM for building muscle mass. In essence, it mimics the action of testosterone in the body. The SARM signals androgen receptors to boost protein synthesis, increase nitrogen retention, enhance lipolysis, and eventually increase strength. This is pretty much everything testosterone does.
Due to their selective action, SARMs only impact the androgen receptors that contribute to performance enhancement or treatment. On the contrary, the receptors are known to cause nasty side effects are left untouched.
Again, to cite the example of LGD-4033.
If you consume an ester of exogenous testosterone, some of the surplus testosterone will be converted to Dihydrotestosterone (DHT), a highly potent androgen. While it is one of the best muscle-building hormones, it is known to cause some of the nastiest side effects known to a bodybuilder (gynecomastia, acne, prostate enlargement, etc.).
SARMs, on the other hand, do not aromatize, nor convert into estrogen. As a result, you are not at risk of gynecomastia, hair loss, acne, or the nasty side effects caused by anabolic steroids. However, you will benefit from their considerable muscle-building potential, which only comes second to that of AS.
Let’s break down each SARM to see how they fare when it comes to building muscle.
If you aren’t familiar with Ostarine, it is often referred to as Enobosarm or MK-2866. On the streets, it has been nicknamed Ostamuscle and Ostabolic. The best part about this SARM is that it is considered to be one of the safest and mildest SARMs, primarily due to numerous human studies and positive user experiences.
Ostarine provides numerous benefits. Overall, it is an excellent compound that can assist you in many ways, including bulking, cutting, and even recomping.
Given that Ostarine was developed to help combat muscle wasting diseases, it has considerable muscle building potential.
This SARM has been flaunted so much as a cutting SARM that it’s muscle-building potential has been overlooked.
If you want to gain mass with Ostarine, experts recommend a four to six-week cycle while taking one dose of 24 to 36 mg per day, for the best results.
Within this time frame, you can gain up to 15 lbs. of lean mass without water retention. Most people are usually concerned about losing their newly acquired muscle after the end of the cycle. If this is your concern, you can take Clomid or Tribestan during the last week of your cycle. This way, you can rest assured that you will not experience any muscle loss after the cycle is complete.
Overall, 30 mg of Ostarine is believed to encourage gains in pure lean muscle, increased protein synthesis, energy, endurance, and increased strength.
Ligand Pharma is the company behind the research and development of Ligandrol, aka LGD-4033. Ligand is one of the most popular SARMs and is widely recommended for building mass (considered to be probably the best SARM for bulking). However, some of its fame hinges on the fact that it is one of the few SARMs that has undergone clinical trials. What’s more, it produced promising results.
When Taking LGD-4033, you should expect nothing short of insane gains in muscle mass and strength.
Results from clinical studies show that test subjects made considerable gains in muscle mass when taking 1 mg per day. That’s right. One milligram. The studies show that the participants gained an average of 3 lbs. of muscle within three weeks. Can you imagine what five milligrams of the SARM can do? What about 10 mg?
Ideally, you want to be experimenting with five milligrams per day. Users have stated that anywhere between 5 mg and 10 mg is excellent for building muscle and gaining strength as well.
LGD has a half-life of approximately 24 hours, which suggests that dosing once a day is adequate.
The amount of mass you gain with Ligandrol or any other SARM for that matter depends on multiple variables, including exercise and diet. For the best bulking results, you are advised to stick to a high protein diet for four days in a week. Unfortunately, not many people can maintain this.
Overall, you expect to gain anywhere from five to ten pounds of lean mass, with minimum bloat, if any.
Technically, Cardarine is not a SARM, although it is often labeled as one. However, it identifies as a PPARδ receptor, instead of an androgen receptor like conventional SARMs. Despite the difference, Cardarine provides results that are just as impressive as you’d get from SARMs.
Cardarine was discovered in the 1990s as a way to prevent and cure tumors. By the early 2000s, researchers from GlaxoSmithKline found that it could treat metabolic disorders, including obesity and diabetes.
Research conducted on Cardarine shows that this substance can lead to increased endurance. Scientist discovered that the PPAR Gene could cause muscle fibers to boost oxygen use. What muscle fibers consume more oxygen, an individual’s endurance levels increase. As a result, you can lift harder and for longer, leading to considerable development of muscle mass.
This compound has also been shown to decrease body fat. Cardarine has been shown to mimic the effects of a growth hormone as it controls the formation of the inflammatory markers in tissue and reduces the activity of the genes involved in lipogenesis. This substance tricks the body into reacting as if it is in starvation. Consequently, the body starts using the fat stored in the body as energy.
PPAR agonists such as Cardarine increase insulin sensitivity, thus increasing the uptake of glucose and amino acids into the skeletal muscles. Consequently, increased entry of amino acids translates to increased protein synthesis, increased muscle hypertrophy, and Growth. This implies that whatever you consume, your body does not store it as carbohydrate or fat. Instead, it is used to develop lean muscle mass.
When it comes to dosing Cardarine, 10 mg per day for eight weeks is useful for building lean muscle mass, boosting anaerobic and aerobic endurance and also assisting with weight loss. The substance has a half-life of 16 to 24 hours. Therefore, a single dose should be enough to take you through the day.
You will love to know that individuals using cuddling to build muscle have reported gains in muscle mass of up to seven pounds within eight short weeks. Overall, individual results differ depending on one’s diet or exercise regime.
As you may have noted, all types of SARMs will contribute to muscle growth. However, some of them will only help in a limited capacity. For instance, Ostarine will prevent muscle loss and cut fat, and also build it but not to a higher degree than Ligandrol.
Overall, SARMs eventually make you stronger, given the potential to help you build lean muscle rapidly. Although you have to work out to acquire most of the gains, they can occur in as little as two weeks. Finally, the changes you will observe in terms of muscle gain differ from one person to another depending on their training schedule, genetics and diet.